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Exosomes: what they are and how they act on the skin
Teresa de Miguel Miró
In recent years, exosomes have sparked growing interest in the field of regenerative medicine and advanced aesthetic medicine. These tiny extracellular vesicles, essential for cell communication, have become an innovative tool for promoting skin repair and rejuvenation processes.
Their application in non-invasive facial protocols has demonstrated significant benefits for skin quality, from improved texture and increased luminosity to a greater capacity for regeneration. In this article, we delve deep into what exosomes are, how they act in the body, and what role they play in skincare.
What are exosomes and what are they used for?
Exosomes are small vesicles (30-140 nanometers) released by cells that contain bioactive information such as proteins, lipids, and genetic material (messenger RNA and microRNA). Their primary function is to act as intercellular communication vehicles, facilitating the transfer of signals between cells to coordinate biological processes such as regeneration, inflammation, or healing.
In the context of aesthetic medicine, exosomes are used for their ability to modulate cellular response and promote tissue regeneration without the need to introduce living cells.

What do exosomes do for the skin?
When applied in aesthetic treatments, exosomes act at the dermal level, triggering a series of regenerative responses:
- They stimulate the synthesis of collagen and elastin, which are fundamental for skin firmness and elasticity.
- They promote cell renewal, improving skin texture and tone.
- They provide anti-inflammatory properties, making them allies for sensitive or irritation-prone skin.
- They favor deep hydration by improving the cells' water retention capacity.
They contribute to greater resistance against oxidative stress, helping to prevent premature aging.
Key aesthetic benefits
Although results may vary depending on skin type, visible and progressive benefits have been observed:
- Optimization of the appearance of post-acne scars or marks.
- Reduction of wrinkles and expression lines thanks to increased collagen production.
- Improvement in luminosity and overall facial appearance.
- Uniformity in skin tone and fading of blemishes.
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Revitalizing effect on dull skin or skin with signs of fatigue.

Frequently asked questions about exosomes in aesthetic medicine
How long does it take to see results?
Visible effects can be seen from the first session, although the most noticeable results usually appear after the third week, as the treatment acts on cellular regeneration processes.
How many sessions are recommended?
The frequency will depend on the skin's condition and the patient's goals. Generally, a protocol of several sessions spaced 3 to 4 weeks apart is recommended.
Can it be combined with other treatments?
Yes, exosomes are easily integrated into protocols combined with techniques such as microneedling or radiofrequency, enhancing their effects.
Is it safe?
Yes. As it is a highly purified treatment without living cells, its use is safe, and adverse reactions are minimal or non-existent.

Is there a gift format available?
For those who wish to offer this type of treatment as an experience, there are specific gift cards for the exosome treatment, valid both as a gift or for self-indulgence. This option allows for flexible enjoyment of the protocol, by appointment.
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